Basic Sciences Core

The mission of the Basic Sciences Core is to develop, refine and provide services and training in relevant basic sciences to DC CFAR investigators. The Core offers virologic and molecular, immunological and imaging services and training that are designed to support basic, clinical and translational research in HIV/AIDS prevention, detection and treatment.

Available Services

Virologic and Molecular Services

Virology Core Laboratory
Veterans Affairs Medical Center
The Virology Core Laboratory offers a wide variety of diagnostic assays for HIV, HCV and STDs at reduced cost.  

Virus Detection and Analysis Laboratory
George Washington University
The Virus Detection and Analysis Laboratory provides services related to analysis of various steps of HIV replication and the effects of anti-HIV compounds and treatments.

RCMI Proteomics Core Laboratory
Howard University
The RCMI Proteomics Core Laboratory allows for the study of functional protein groups as well as protein structure and function.

Molecular Modeling and Drug Discovery Core Laboratory
Howard University
The Molecular Modeling and Drug Discovery Core Laboratory helps bridge the divide between bench discoveries and hospital bedsides by identifying and testing novel drugs.

NGS CFAR Core Laboratory
George Washington University
The NGS CFAR Core Laboratory provides NextGen Sequencing assays on the MiSeq NGS instrument for HIV and HCV for the DC CFAR investigator community.

Immunologic Services

Flow Cytometry and Cellular Immunology Core Laboratory
The George Washington University, Children’s National Medical Center
The Flow Cytometry and Cellular Immunology Core Laboratory allows investigators to count, sort, characterize and identify cells.

Multiparametric Flow Cytometry Core Laboratory
The George Washington University
The Multiparametric Flow Cytometry Core Laboratory provides advanced flow cytometry capacity that compliments previously available technology.

Biacore Molecular Interaction Shared Resource (BMISR)
Georgetown University
The Biacore Molecular Interaction Shared Resource studies the binding kinetics of protein-protein, protein-DNA or protein-small molecule interactions.

Imaging Services

Microscopy and Imaging Core Laboratory
The George Washington University
The Microscopy and Imaging Core Laboratory provides the ability to prepare samples, collect images of live or fixed cells and conduct live-cell time-lapse studies using well established techniques specific to HIV research.

Center for Functional and Molecular Imaging (CFMI)
Georgetown University
The Center for Functional and Molecular Imaging integrates advanced MRI, EEG and NIRS to study physiological changes associated with HIV/AIDS in research participants.

Research Pathology Core Laboratory
George Washington University
The Research Pathology Core Laboratory provides histology and pathology services for DC CFAR clinical and basic science investigators.

Core Manager

Core Directors

Douglas F. Nixon, MD, PhD
Core Director
202-994-3532
dnixon@gwu.edu

 

Sergei Nekhai, PhD
Core Co-Director
202-865-4545
snekhai@howard.edu