Sergei Nekhai, PhD

Title:
Professor, Department of Medicine, Howard University
Phone: 202-865-4545
Email:
snekhai@howard.edu

Current HIV/AIDS Research Activities:

  • Regulation of HIV-1 transcription by host cell CDK2 and protein phosphatase-1
  • Effect of iron chelators and hypoxia on activation of HIV-1 transcription
  • Design of small molecule inhibitors of HIV-1 Tat-protein phosphatase-1 interaction and HIV-1 transcription
  • Effect of abnormal hypoxic response in Sickle Cell Disease and Chuvash polycythemia in development of pulmonary hypertension

Current HIV/AIDS Educational Activities:

  • Virology Course (viral structure, immunology and pathogenesis) for graduate students, Department of Microbiology, Howard University
  • Viral Diagnostics in Microbiology for Nursing Students, Department of Microbiology, Howard University
  • Supervision of graduate students (total 8 minority Ph.D. students for the past 10 years); postdoctoral fellows and junior faculties

Current HIV/AIDS Clinical Activities:

  • Journal reviewer: Journal of Biological Chemistry; Retrovirology; American Society for Cancer Research; Future Medicine; Current HIV-1 Research; Nature Microbiology Reviews; Gene Therapy; Journal of Molecular Medicine; Journal of Cellular Physiology;
  • Grant reviewer: AIDS Fonds (Netherlands)
  • Grant reviewer: National Institutes of Health
  • Direct Proteomics Core Facility for Howard University
  • Direct analysis of hemoglobin using HPLC (free service for community)