Keylie Gibson (GW) along with DC CFAR and DC Cohort Investigators Drs. Kamwing Jair (GW), Amanda Castel (GW), Jeanne Jordan (GW), Keith Crandall (GW), Marcos Perez-Losada (GW) and with colleagues from the DC Cohort published an article in Nature Scientific Reports in February 2020 entitled " A cross-sectional study to characterize local HIV-1 dynamics in Washington, DC using next-generation sequencing."
The study examined local phylodynamics of HIV-1 in DC using next-generation sequencing (NGS) and epidemiological data from a subset of DC Cohort participants to better understand the HIV-1 epidemic. This group of investigators had previously looked at the historical diversity of HIV in Washington DC, whereas this paper focuses on the current phylodynamics of HIV transmission in DC. The results from this study compared to previous analyses provides a better understanding of local HIV-1 transmission since it "evaluates multiple genes together rather than focusing on polymerase genes". In addition, the authors looked at "phylogenetic and network inferences, drug-resistant mutations (DRMs), subtypes and HIV-1 diversity". The study was supported by a 2015 HIV-1 Phylodynamics Supplement award and the DC Cohort