Immunology, Virology and Pathogenesis

The DC CFAR supports research in HIV immunology, virology and pathogenesis. Active areas of research include latency, cure and vaccine development, cholesterol metabolism and HIV-1 evolutionary dynamics.

Active NIH Funding

A Novel FMRI Biomarker of Asymptomatic HIV-Associated Neurocognitive Disorders: 5R01MH108466-02
Xiong Jiang, PhD
Georgetown University
AIDS and Cancer Specimen Resource (ACSR): 4UM1CA181255-04
Sylvia Silver, DA
The George Washington University
Inhibition of HIV-1 in Sickle Cell Disease: 5R01HL125005-03
Sergei Nekhai, PhD
Howard University
Mechanisms of Pediatric HIV Neurological Impairment: 5R03MH107261-02
Mark Burke, PhD
Howard University
Long-term Immunity Against Toxoplasmosis: 2R01AI033325-21A1
Imtiaz Khan, PhD
The George Washington University
Metabolic Complications of HIV Disease Caused by NEF Released from HIV-infected Cells: 1R01HL131473-01
Michael Bukrinsky, MD, PhD
The George Washington University
Structural Characterization of the NEF-Calnexin Complex: 1R21AI114471-01A1
Michael Bukrinsky, MD, PhD
The George Washington University
DEVELOPING PATHOGEN RECOGNITION RECEPTOR AGONISTS AS LATENCY REVERSING AGENTS: 5R01AI124722-03
Alberto Bosque-Pardos, PhD, MBA
The George Washington University
Accelerated Aging of Microvessels and Perivascular Adipose Tissue in Women with HIV: 1R01HL134511-01
Dan Wang, MD, PhD
Georgetown University
Role of Cytokines and APOL-1 in the Pathogenesis of Childhood HIV Associated NEPH: 5R01DK103564-02
Patricio Ray, MD
Children's National Medical Center
Pathogenesis of Chronic Renal Injury and Hypertension in HIV-infected Children: 1R01DK108368-01
Patricio Ray, MD
Children's National Medical Center
REPLICATION COST TO HIV-1 AFTER ESCAPE FROM BROADLY NEUTRALIZING ANTIBODIES: 5K22AI114299-02
Rebecca Lynch, PhD
The George Washington University
Role of bfgf Low Affinity Receptors in Childhood HIVAN: 2R01DK049419-15
Patricio Ray, MD
Children's National Medical Center
GP120 BINDS TO NEURONAL MICROTUBULES: A NEW MECHANISM FOR SYNAPTIC SIMPLIFICATION: 1R21NS104000-01
Italo Mocchetti, PhD
Georgetown University
A FAMILY OF COMPOUNDS THAT REACTIVATE LATENT HIV WITHOUT T CELL ACTIVATION: 5R33AI116212-05
Alberto Bosque, PhD, MBA
The George Washington University
CHARACTERIZATION OF COCAINE INDUCED SIGNALING PATHWAYS THAT ENHANCES HIV TRANSCRIPTION: 1R01DA041746-01
Mudit Tyagi, PhD
The George Washington University