Research Pathology Core Laboratory

The Research Pathology Core Laboratory is available to provide histology and pathology services for DC CFAR clinical and basic science investigators.  Our mission is to provide quality histological tissue preparation and processes in a timely and cost-efficient manner for research cell and tissue specimens, including frozen sections, tissue processing, embedding, sectioning, routine H&E and special stains, frozen sections and Immunohistochemistry.  The lab can also provide expertise in-house to assist investigators in developing new histological approaches that can further their research productivity.

Services and Instrumentation

  • Histology - Processing of cells and tissues to formalin-fixed paraffin-embedded (FFPE) specimens and tissue sections includes fixation, processing, embedding, and sectioning for routine histology. Routine H&E staining and special stains are available. Cryosectioning is provided for frozen tissue.
     
  • Immunohistochemistry - Services include manual immunohistochemical staining with established antibodies, and optimization of new antibodies, using a variety of detection systems.  Immunofluorescent staining is also available.  
     
  • Necropsy- Assistance with gross examination, animal tissue harvest or specific tissue collection can be provided, with trimming of tissues as determined in consultation.
     
  • Pathology - Pathology consultative services are available for studies using human tissues and animal models, including recommendations on histologic methods and interpretations of pathology or immunological stains, as determined by an investigators need and available expertise.

To request core laboratory services, please complete the Core Service Request Form or contact the Core Manager. Additional information about available services can be found in the available laboratory documents.

Leadership

The Director of the GWU Research Pathology Core Laboratory is Patricia Latham, MD, EdD, who is a member of the Department of Pathology at GWU-SMHS. Dr. Latham is available to consult with DC CFAR members on the development of protocols and grant applications that may use the resources of the laboratory.