DC CFAR member, Mimi Ghosh, PhD, MS has published an article along with her co-authors in the American Journal of Obstetrics and Gynecology entitled,"Reduced levels of genital tract immune biomarkers in postmenopausal women: implications for HIV acquisition".
The article discusses the results of a study comparing levels of female reproductive immune mediators important for HIV-associated immune responses, as well as inherent anti-HIV activity in cervical vaginal specimens collected from HIV-negative pre- and postmenopausal women. According to the article, the findings suggest that the female reproductive tract immunity is distinct in the HIV-negative postmenopausal women, and further studies are needed to assess the risk of HIV acquisition and transmission in this population.
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