Photo of Ivan Tong Mak

Ivan Tong Mak, PhD

Research Professor, Departments of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, The George Washington University
Phone: 202-994-2865
[email protected]

Current HIV/AIDS Research Activities:

  • HAART-and HIV- induced cardiovascular toxicity, metabolic effects and therapy:
    • In vitro endothelial cytotoxic mechanisms of HAART drugs (NRTIs, NNRTIs, and Protease inhibitors)
    • In vivo systemic oxidative/nitrosative and neurogenic inflammation and metabolic lipid disturbances induced by combination ART regimen leading to cardiac pathology and contractile dysfunction in HIV-transgenic rat model.
    • Potential protective effects and mechanisms of Mg-supplements